A Review on the Relevance of Curcuminoids in Corona Pandemic Situation
International Research Journal on Advanced Science Hub,
2020, Volume 2, Issue Special Issue ICARD 2020, Pages 291-297
AbstractA hyperactive response by the immune system is said to be primarily responsible for pneumonia, also a fall out of a severe SARS-CoV-2 infection. Infection starts when the viral spike protein binds to its complementary host cell receptor. Viruses from the corona primarily attack epithelial cells. Depending on the species of the corona virus, they are transmitted from one host to another by either an aerosol, fomite, or faecal-oral route. Chloroquine and hydroxychloroquine are interferon blockers but they increase the risk of unsafe heart rhythm disturbances. Curcumin, a photochemical which occurs naturally in Curcuma longa, is known to have strong pharmacological properties.But it is essential to overcome the limitations for using it in medication. By docking, curcumin and its derivatives were shown to have the capacity to serve as spike protein inhibitors and thus viral entry.In this review, papers focused on structure, platforms and ill effects of Corona virus, and also discloses the nutrients which include mainly poly phenols and antioxidants containing curcuminoids which has antivirus and anti inflammatory properties; the nutrients under discussion can support the healthy functioning and strengthening of the respiratory system.
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