Diclofenac is an anti-inflammatory, non-steroidal drug used to treat pain and inflammatory disorders such as gout. Since diclofenac is not fully absorbed in the body, it is apparent that a part of it is defecated and enters the aqueous system. Diclofenac may also be fed to the natural environment by waste from the pharmaceutical industry. Diclofenac 's presence in nature may have adverse effects on living organisms. In reality, human life and the health of natural ecosystems can be widely jeopardized. Therefore, various remediation techniques, like advanced oxidation processes, membrane filtration, biological treatment, electro-coagulation etc., are reviewed and contrasted in this review paper in order to eliminate diclofenac from the waste water or reduce its life to a minimum. Though, currently, many conventional techniques are being used for the removal of such persistent compounds but more advanced techniques should be introduced to mitigate the environmental and human health risk.